Microbiology TEST 2
Lectures 5 - 7
Lectures 5 - 7
Set of flashcards Details
| Flashcards | 343 |
|---|---|
| Language | English |
| Category | Biology |
| Level | University |
| Created / Updated | 28.11.2016 / 06.02.2020 |
| Weblink |
https://card2brain.ch/box/parasitologie_laboratory_diagnosis
|
| Embed |
<iframe src="https://card2brain.ch/box/parasitologie_laboratory_diagnosis/embed" width="780" height="150" scrolling="no" frameborder="0"></iframe>
|
Create or copy sets of flashcards
With an upgrade you can create or copy an unlimited number of sets and use many more additional features.
Log in to see all the cards.
Ect-hyma gangrenosum caused by which non-fermentative bacteria ?
pseudomonas aeruginosa - due to elastase
Pseudomonas aeruginosa clinical presentation:
→BE PSEUDO Cool MEN
B – Burn & Wound infections
E – Endocarditis in IV drug abusers (IV= intravenous)
P- pneumonia in cystic fibrosis & immunocompremised
S- Sepsis caused by soft tissue, skin, UT & LRT infections
E- External malignant otitis media in diabetic patients
U- UTI
DO – diabetic osteo-chondritis (inflammation of bone&cartilage)
C- Corneal Infections (corneal ulcers)
MEN- Meningitis
Pseudomonas aeruginosa in cystic fibroses patients lead to which clinical presentation?
pneumonia
Pseudomonas aeruginos leads to External otits name its synonym?
swimmer's ear
Swimmer's ear/external otitis is caused by which bacteria?
pseudomonas aeruginosa
Pseudomonas aeruginosa Virulence Factors:
Elastase
Phospholipase C – is a hemolysin
Proteases
Exotoxin A,S,T
Pyo-cyanin– blue pigementation – catalyse production of H2O2&superoxide
Pyo-verdin– green pigmentation
Adhesins: pili, flagella,
CAPSULE– alginate is a mucoid exopolysaccharide forms capsule
LPS – endotoxin
Name all hospital-acquired gram-negative bacteria:
-> not part of natural flora
What sort of infection does Burkholderia cepacia primarily cause?
Primarily opportunistic infections = restricted to patients receiving broad-spectrum antibioticsthat suppress normal intestinal flora
Which two bacteria cause primarily opportunistic infections ?
Burkholderia cepacia
Pseudomonas aeruginosa
Burkholderia cepacia reservoir
ubiquitous in environment
in CF patients (cystic fibrosis)
Which patients are highly susceptible for infection with Burkholderia cepacia
cystic fibrose patients– pneumonia + bacteremia
patients with CGD – chronic granulomatous disease
Clinical presentation of Burkholderia cepacia:
pulmonary infections
bacteremia
UTI
Name the opportunistic infections that burkholderia cepacia can cause
Steno-tropho-monas malto-philia clinical presentation
→ leads to nosocomial infections = opportunitsic infections in hospitalized patients – hospital-acquired infections
USUALLY= Bacteremia & Pneumonia
Acine-to-bacter baumannii similar clincial presentation as pseudomonas aeruginosa:
→ opportunistic pathogens – hospital-acquired infections
- Pneumonia
- bacteremia
- UTI
- Burn-wound infections
- Eye infections
Leptospira has 2 species name them:
Leptospira interrogans - pathogenic species
Leptospira biflexa - saprophytes
Name non-flexible spiral bacteria
- helicobacter
- campylobacter
- vibrio
Name flexible spiral bacteria
- Treponema
- Borrelia
- Leptospira
Where is endoflagella ?
- characteristic ONLY in spirochetes
- under the phospholipid-rich outer membrane - protects from immune recognition
- in periplasm
Endoflagella also known as ?
axial filament
Function of axial filament
- rotation of flagella spins the spirochete around
- generates corkscrew type movement
Composition of flexible spiral bacteria from inner sheath to outer
- innermost portion: cytoplasmic membrane
- 2nd layer: Cell Wall or periplasmic layer
- 3rd : periplasmic space with endoflagella
- 4th: outer membrane - surrounding endoflagellla and protects from immune recognition
Virulence factors of flexible spiral bacteria
- Motility - active penetration into tissue
- low immunity - protect from immune recognition
- OMP - adhesion
- fibronectin-binding - anti-phagocytic
- hyaluronidase
- endothelial cells damage - inflammation
flexible spiral bacteria - spirochete - bacteria with endoflagella/axial filament
Leptospira reservoir
Leptospira transmission
Leptospira penetrate human through
- intact mucous membrane
- or scretched skin (abresions - schürfwunde)
- or conjunctiva
Leptospirosis can be
Leptospira interrogans causes a more severe illness of leptospir-osis
Most important species of Mycoplasma ?
Mycoplasma pneumonia - Eaton agent
Mycoplasma pneumoniae also named
Eaton agent
-
- 1 / 343
-
