Applied Physiology

Chapter 19: The Cardiovascular System: The Blood

Chapter 19: The Cardiovascular System: The Blood


S. D.
This flashcard set covers advanced topics in physiology at the university level, focusing on the composition and functions of blood, including its cells, plasma, and proteins. It delves into the transport of substances like oxygen and carbon dioxide, the regulation of pH and body temperature, and the protective roles of blood components. Medical students and healthcare professionals will find this set particularly useful for understanding the intricate workings of the circulatory system and its impact on overall health.
Karten
17
Lernende
1
Sprache
Englisch
Kategorie
Medizin
Stufe
Universität
Erstellt / Aktualisiert
06.09.2015 / 20.09.2015

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Blood 

liquid connective tissue that consists of cells surrounded by a liquid extracellular matrix

Extracellular matrix

called blood plasma, and it suspends various cells and cell fragments

Three General Functions of Blood 

Transportation: trasports oxygen from lungs to cell bodies ad carbon dioxide from cell bodies to luns for exhalation. Carries nutrients and hormone to cell bodies and heat and waste products to e eliminated from body

Regulation: regulate ph, body temperature 

Protection: clot formation, white blood protect against disease

Physical Characteristics of Blood

Denser and thicker than water and feels slightly sticky. 

Temp 38C (100.4F)

AlkalinePH 7.35-7.45

Color: Oxgenated-> Bright Red, Unsaturated with Oxgen: dark red 

Blood Volume: Average male->5-6Liters, Average Woman-> 4-Liters 

Components of Blood: Blood Plasma 

a watery liquid extracellular matrix that contains dissolved substances

Components of Blood: Formed Elements

are cells and cell fragments 

45% of blood 

Substances in Blood Plasma 

Water (91.5%) : liquid portion of blood. Solvent and suspending medium. Absorbs, transports, and releases heat. 

Plasma proteins (7%): Most produced by liver. Responsible for collid osmotic pressure. Major contributors to blood viscosity. Transport hormones (steroid), fatty acids, and calcium. Help regulate blood pH

Albumins: Smallest and most numerous plasma proteins. Help maintain osmotic pressure, an important factor in the exchange of fluids across blood capillary walls. 

Globulins: Large proteins (plasma cells produce immunoglobulins) Immunoglobulins help attack viruses and bacteria. Alpha and beta globulins transport iron, lipids, and fat-soluble vitamins

Fibrinogen: Large protein Plays essential rold in blood clotting.

Other Solutes (1.5%)

Electrolytes: Help maintain osmotic pressure and play essential roles in cell functions 

Nutrients: products of digestion, such as amino acids, glucose, fatty acids, glycerol, vitamins, and minerals. Essential roles in cell functions, growth, and development.

Gases: Oxygen:Important in many cellular functions., Carbon Dioxide: Involved in the regulation of blood pH, Nitrogen: No known function.

Regulatory Substances: Enzymes: Catalyze chemical reactions, Hormones: Regulate metabolism, growth and development, Vitamins: Cofactors for enzymatic reactions

Waste products: Most are breakdown products of protein metabolism that are carried by the blood to organs of excretion  

Three principle components of formed elements of blood

Red Blood Cells (RBCs) (Erythrocytes): transport oxygen from the lungs to body cells and deliver carbon dioxide from body cells to the lungs

White Blood Cells (WBCs) (leukocytes): protect the body from invading pathogens and other foreign substances. Neutrophils, basophils, eosinophils, monocytes. Lymphocytes: B lymphocytes (Bcells), T lymphocytes (tcells), and natural killer (NK) cells. 

Platelets: fragments of cells that do not have nucleus. Release chemicals that promote blood clotting 

Hematocrit

Percentage of total blood volume occupied by RBCs 

Normal range females: 38-46%

Normal range males: 40-54%

anemia

lower than number of RBCs 

Polycythemia

65% or higher  RBC. Raises the viscoosity of blood. 

Which of the following blood cells are INCORRECTLY matched with their functions?  

A lower than normal hematocrit may indicate anemia while a higher than normal hematocrit may indicate polycythemia.

Which of the following statements is INCORRECT?

Blood transports which of the following substances?

How many kilograms or pounds of blood does your body contain?

Hemopoiesis/ Hematopoiesis

process by which formed elements of blood develop 

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