Pharma m6

A hydantoin drug that is extensively protein bound & follows zero-order kinetics at high doses.

Not a DOC for Grand mal & partial seizures.

DOC for Grand mal, petit mal & myoclonic and atypical absence seizure.

Not a DOC for partial seizure

Not a DOC for status epilepticus

DOC for Grand mal, partial seizures & status epilepticus.

Known toxicities of this drug is diplopia, ataxia, gingival hyperplasia, hirsutism & fetal hydantoin syndrome.

A child has the following features upturned nose, mild midfacial & lower distal digital hypoplasia, long upper lip with thin vermillion border. What drug is the most likely culprit?

A tricyclic drug that works by blocking the Na+ channels. It is a DOC for Grand mal, partial seizures & in trigeminal neuralgia.

This drug is known to cause diplopia, ataxia, blood dyscrasia, SJS, & erythematous rash.

A branched-chain fatty acid that blocks the high-frequency firing of neurons modifying the amino acid metabolism.

The DOC for Grand mal, acute mania & juvenile myoclonic epilepsy.

This drug is known to cause GI distress (m/c), hepatotoxicity (infants), neural tube defects & spina bifida.

An inhibitor of CYP450 enzymes.

A barbiturate drug that bind to GABAa receptor, increasing the duration of Cl channel opening. This is the preffered antiseizure drug for pregnant women & children.

This drug is known to cause dependence liability & acute intermittent porphyria.

A cyclic ureide that decreased the threshold of Ca++ currents (T-type) in thalamus.

The DOC for absence seizures (petit mal) & known to cause GI distress.

A GABA derivative drug that mainly blocks Ca++ channels (N-type). Increases GABA but decreases glutamate release.

Used mainly for treatment of neuropathic pain & migraine and as an adjunct for partial seizures. M/c adverse effects are dizziness, sedation, ataxia, nystagmus & tremor.

A piracetam drug that selectivelu binds synapyic vesicular protein SV2A. This drug is known to cause irritability, hallucination, sedation & psychosis.

A substituted monosaccharide anti-seizure drug that has the most number of mechanism of action.

Used for treatment of Grand mal, petit mal & partial seizures, Lennox-Gastaut syndrome, West syndrome & migraine.

This drug is known to cause psychomotor slowing, memory impairment, weight loss, acute myopia, glaucoma & urolithiasis.