-
-
- 1 / 105
-
Cartes-fiches
Fluvoxamin
Substrat: CYP1A2, CXP2D6
Inhibitor: CYP1A2, CYPC19, CYPC9, CYP2D6
in vivo
Furafyllin
Substrat: CYP1A2
Inhibitor: CYP1A2
in vitro
Koffein
Substrat: CYP1A2 und der N-Acetyltransferase (NAT2) und Xanthinoxidase
Phenacetin
Substrat: CYP1A2
Theophyllin
Substrat: CYP1A2, NAT2, und Xanthinoxidase
Cumarin
Substrat: CYP2A6
Nikotin
Substrat: CYP2A6
Methoxsalen
Inhibitor: CYP2A6
mechanismus basiert, in vitro
Tranylcrypromin
Inhibitor: CYP2A6
irreversibel
Bupropion
Substrat: CYP2B6
Efavirenz
Substrat: CYP2B6
Cerivastatin
Substrat: CYP2C8
Ticlipidin
Inhibitor: CYP2B6, CYP2C19
zeitabhängig
Repaglinid
Substrat: CYP2C8
Gemfibrizol
Inhibitor: CYP2C8
zeitabhängig, mechanismus basiert
Montelukast
Inhibitor: CYP2C8
kompetitiver inhibitor, in vitro
Diclofenac
Substrat: CYP2C9
Losartan
Substrat: CYP2C9
S-Warfarin
Substrat: CYP2C9
Tolbutamid
Substrat: CYP2C9
Sulfaphenazol
Inhibitor: CYP2C9
in vitro
Ticrynafen
Inhibitor: CYP2C9
in vitro, mechanismus und zeitbasiert
Fluconazol
Inhibitor: CYP2C9, CYPC19, CYP2D6 und CYP3A4
in vivo
Clopidogrel
Substrat: CYP2C19
S-Omeprazol
Inhibitor: CYP2C19
mechanismus basiert, zeitabhängig, in vitro und in vivo
Omeprazol
Substrat: CYP2C19
Inhibitor: CYP2C19
S-Mephenytoin
Substrat: CYP2C19
Codein
Substrat: CYP2D6, CYP3A4 und UGT2B7
Debrisoquin
Substrat: CYP2D6
Metroprolol
Substrat: CYP2D6
Spartein
Substrat: CYP2D6
Taoxifen
Substrat: CYP2D6
Chinidin
Inhibitor: CYP2D6, P-Glykoprotein, Inhibitor des Enzymsystems
Substat: P-Glykoprotein
in vitro
Paroxetin
Inhibitor: CYP2D6
zeitabhängig, mechanismus basiert
Acetaminophen
Substrat: UGT, SULT, CYP2E1, CYP3A4
Chlorzoxazone
Substrat: CYP2E1
Fomepizol
Inhibitor: CYP2E1, Alkoholdehydrogenase
in vitro
Dextromethorphan
Substrat: CYP3A4, CYP2D6
Erythromycin
Substrat: CYP3A4
17-alpha Ethinylestradiol
Substrat: CYP3A4
