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Erstellt / Aktualisiert 28.04.2020 / 20.04.2021
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Fenster schliessen

An example of a non-specific activation of immunity in the cancer

immunotherapy, is:

the use of monoclonal antibodies conjugated with radioisotopes

the use of vaccines containing tumor antigen-encoding DNA

vaccines containing professional APCs, transfected with genes encoding the cancer antigens

the use of cytokines, such as IL-2, IFN-gamma

the use of monoclonal antibodies conjugated with cytostatics

Fenster schliessen

A naïve lymphocyte, this is a cell which can subsequently turn into

Effector cell

Macrophage

Mast cell

Dendritic cell

Fenster schliessen

An FAB fragment of an Immunoglobulin:

determines the antibody class

determines the antibody subclass

determines the epitope binding properties

determines the complement activation capacity

determines the effectore cellbinding capacity

Fenster schliessen

T CD4+ lymphocyte recognize foreign antigens usually in:

MHC class I restriction

MHC class II restriction

MHC class I and II restriction

Without MHC molecules

Fenster schliessen

The immunofluorescence in flow cytometry can be describes as

The intensity of the emitted florescence is proportional to the number of XXX

The intensity of the emitted florescence is proportional to the number of antigens that bind fluorochrome-labelled antibodies

The intensity of the emitted florescence is proportional to the number antigens binding a fluorochrome

The intensity of the emitted florescence is proportional to the size and granularity of cells

Fenster schliessen

Antigenic determinant is a

paratope

epitope

idiotype

Fenster schliessen

Immunophenotype typical markers for NK cells are:

CD45, CD3

CD19, CD20

CD56, CD16

CD4, CD8

Fenster schliessen

B-cell receptor (BCR), this is:

a soluble antibody

an antibody anchored in the cell membrane

an opsonin receptor

a receptor for the cytokine