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An example of a non-specific activation of immunity in the cancer
immunotherapy, is:
the use of monoclonal antibodies conjugated with radioisotopes
the use of vaccines containing tumor antigen-encoding DNA
vaccines containing professional APCs, transfected with genes encoding the cancer antigens
the use of cytokines, such as IL-2, IFN-gamma
the use of monoclonal antibodies conjugated with cytostatics
A naïve lymphocyte, this is a cell which can subsequently turn into
Effector cell
Macrophage
Mast cell
Dendritic cell
An FAB fragment of an Immunoglobulin:
determines the antibody class
determines the antibody subclass
determines the epitope binding properties
determines the complement activation capacity
determines the effectore cellbinding capacity
T CD4+ lymphocyte recognize foreign antigens usually in:
MHC class I restriction
MHC class II restriction
MHC class I and II restriction
Without MHC molecules
The immunofluorescence in flow cytometry can be describes as
The intensity of the emitted florescence is proportional to the number of XXX
The intensity of the emitted florescence is proportional to the number of antigens that bind fluorochrome-labelled antibodies
The intensity of the emitted florescence is proportional to the number antigens binding a fluorochrome
The intensity of the emitted florescence is proportional to the size and granularity of cells
Antigenic determinant is a
paratope
epitope
idiotype
Immunophenotype typical markers for NK cells are:
CD45, CD3
CD19, CD20
CD56, CD16
CD4, CD8
B-cell receptor (BCR), this is:
a soluble antibody
an antibody anchored in the cell membrane
an opsonin receptor
a receptor for the cytokine
