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Cartes-fiches 177 Cartes-fiches
Utilisateurs 34 Utilisateurs
Langue English
Niveau Université
Crée / Actualisé 28.04.2020 / 20.04.2021
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To assess T cell proliferation there should be used:

Tritiated thymidine incorporation test

NBT absorption and reduction test

Radial immunodiffusion test

Tryptan blue staining test

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To assess the presence of anti-eurythrocyte antibodies in blood

serum, the follow- ing test can be used

Direct Coombs test who already bound to the surface of RBC

Indirect Coombs Test

none of above

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To detect an enzyme defect in the neutrophil oxidative

metabolism, the following test is used:

50% hemolysis CH50 test

Tryptan blue staining test

Nitroblue tetrazolium (NBT) reduction test

Radioactive chromium 51Cr release test

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To distinguish general population of NK cells and T cells, the

surface markers should be:

CD4, CD8, CD16

CD3, CD14, CD56

CD3, CD45, CD56

CD4, CD16, CD56

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To identify populations of monocytes and T-helper cells in PBMC’s,

most probably there should be assessed:

CD3 CD4 CD45

CD3 CD8 CD25

CD4 CD16 CD56

CD4 CD14 CD45

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To identify populations of NK cells and T-cell in the peripheral

blood cell population there should be assessed:

CD3 CD45 CD56

CD4 CD8 CD16

CD3 CD4 CD19

CD3 CD14 CD56

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Typical non-specific immune response cells are:

macrophages, NK cells

macrophages, T and B lymphocytes

T lymphocytes

dendritic cells, T cells

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Which of the following chemical compounds does not arise after

activation of NADPH oxidase in the pathogen elimination process

The O2

H2O2

O2

NO

OH-

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Which of the following descriptions of the immune response

should not be referred to HYPERRACTIVITY:

excessive

predictable

specific

to a harmful stimulus

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Which of the following statements is NOT true:

B cells - recognize and present protein antigens to T helper cells

NK cells - able to cytotoxicity

T cells- able to phagocytosis

Dendritic cells - present antigens to T helper cells

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Which of the following statements, describing the essential activities of cells involved

in the immune response, is false:

B lymphocytes- recognize and present peptide antigens to helper T lym- phocytes

NK cells- have the cytotoxicity capacity

T lymphocytes- have the cytotoxicity and phagocytosis capacity

Dendritic cells- present antigens to helper T lymphocytes

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Which of the properties characterizes the specific immune response against the

thymus dependent antigens:

Synthesis of antibodies requires the cooperation of T cytotoxic cells

Synthesis of antibodies requires the cooperation of PRR

The antigen are produced in the thymus

The antibodies are mainly in the IgG1 and IgG3 class

The antibodies are mainly in the IgM class

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Which of the statements describing the essential activities of cells participating

in an immune response is WRONG:

Dendritic cells - present antigens to auxiliary lymphocytes

NK cells - capable of specifically identifying cells infected with the virus

Eosinophile - capable of controlling parasites

B-lymphocytes recognize protein antigens presenting auxiliary lymphocytes

Tc lymphocytes capable of cytotoxicity and production of perfumers and granzymes

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Which of the substances present in NK cells cytoplasmic granules,

is responsible for the cytotoxic activity of the cells

properdin

C3

Lysozyme

IL-1

Perforin

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Which type of hypersensitivity best describes neonatal hemolytic

disease caused by incompatibility in the Rh range:

anaphylactic

Cytotoxic

Immune complexes

Delayed

Atopic

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Antigenicity, this is

The feature of a paratope that conditions its capacity of being specifically recognized by antibodies

The feature of an antigen that conditions its capacity of specific immune response activation

The feature of an epitope that conditions its capacity of being specifically recognized by a paratope

The feature of an antigen that conditions its capacity of being specifically recognized by an antigen determinant

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A blood smear, this is a test aimed basically to assess:

Red blood cell count

Hemoglobin amount

Platelets count

White blood cell pattern

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The essential elements of the specific recognition in the immune system are

An antigen, an antibody, the complement

An Antibody, a BCR, a TCR

An epitope, a paratope, the complement

A MHC, a HLA, a denditric cell

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A Cell that encounters an antigen for which it has a specific receptor may finally:

Be activated to an effector cell

Be activated into a memory cell

be inactivated and/or undergo apoptosis

Ignore presence of the antigen

All correct

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The acquired immune response can be characterized by the below

features with the EXCEPTION of

High specificity

Immune memory

Invariability

High variability

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A Fab composition in an antibody

(->  allotopes, which are non-varying structures on the Fc receptor.)

determines antibodies class

determines antibody sub class

determines the epitope binding capacity?

determines the antibody allotrope?

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To identify populations of NK cells and T-cell in the peripheral

blood cell population, there should be assessed

(Midterm Set II)

CD3, CD45, CD56

CD4, CD8, CD16

CD3, CD4, CD19

CD3, CD14, CD56

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A HIV infection diagnostic procedure referred to as a confirmation

test should be

ELISA (detection of anti-gp 120)

Western blot

ELISA (detection of anti-p24)

Flow cytometry (immunophenotyping of CD4+, CD8+, CD20 + cells)

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The phagoburst test in the flow cytometry allows

(Midterm Set III)

To determine the number of viable cells that are capable to absorb bacteria

To determine the number of fluorescent-labelled bacteria, phagocytes by a single phagocyte

To assess the formation of reactive oxygen species by Nitroblue tetrazolium reduction to formazans in phagocytes

To assess the formation of reactive oxygen species by substrate oxidation to a fluorescent compound in phagocytes

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A humoral response is targeted on:

Both thymus-dependent and thymus-independent antigens

Exclusively thymus-dependent antigens

Exclusively thymus-independent antigens

Exclusively pathogen antigens

Exclusively haptens

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After a density gradient PBMC isolation, the cell viability must be

assessed. The proper dye is

(Midterm Set III)

Nitroblue tetrazolium (NBT)

Blue formazans

Trypan blue

CFSE

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A Peyer's patch, this is:

encapsulated organ of gastrointestinal tract lymphatic tissue

non-encapsulated structure of gastrointestinal tract lymphatic tissue

Waldeyer's ring component

A microfolded cell (M-cell)

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Select the set of surface antigens that best characterize NKT cells

(Midterm Set III)

CD3-, CD16+, CD45+, CD56+

CD3-, CD14+, CD16+, CD45+

CD3+, CD16+, CD45+, CD56+

CD3+, CD19+, CD45+, CD56+

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A test applied to detect the oxygen metabolism enzyme defect

should be:

50% hemolysis- CH50

Trypan blue uptake

Nitroblue tetrazolium reduction test (NBT)

Radioactive chromium release assay

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The set of antigens that comprise different cell molecules,

associated with its differentiation, maturation and function is

termed as

(Midterm Set III)

Immunophenotype

Genotype

Idiotype

Allotype