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Erstellt / Aktualisiert 28.04.2020 / 20.04.2021
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Fenster schliessen

Antigenicity, this is

The feature of a paratope that conditions its capacity of being specifically recognized by antibodies

The feature of an antigen that conditions its capacity of specific immune response activation

The feature of an epitope that conditions its capacity of being specifically recognized by a paratope

The feature of an antigen that conditions its capacity of being specifically recognized by an antigen determinant

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A blood smear, this is a test aimed basically to assess:

Red blood cell count

Hemoglobin amount

Platelets count

White blood cell pattern

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The essential elements of the specific recognition in the immune system are

An antigen, an antibody, the complement

An Antibody, a BCR, a TCR

An epitope, a paratope, the complement

A MHC, a HLA, a denditric cell

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A Cell that encounters an antigen for which it has a specific receptor may finally:

Be activated to an effector cell

Be activated into a memory cell

be inactivated and/or undergo apoptosis

Ignore presence of the antigen

All correct

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The acquired immune response can be characterized by the below

features with the EXCEPTION of

High specificity

Immune memory


High variability

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A Fab composition in an antibody

(->  allotopes, which are non-varying structures on the Fc receptor.)

determines antibodies class

determines antibody sub class

determines the epitope binding capacity?

determines the antibody allotrope?

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To identify populations of NK cells and T-cell in the peripheral

blood cell population, there should be assessed

(Midterm Set II)

CD3, CD45, CD56

CD4, CD8, CD16

CD3, CD4, CD19

CD3, CD14, CD56

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A HIV infection diagnostic procedure referred to as a confirmation

test should be

ELISA (detection of anti-gp 120)

Western blot

ELISA (detection of anti-p24)

Flow cytometry (immunophenotyping of CD4+, CD8+, CD20 + cells)

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The phagoburst test in the flow cytometry allows

(Midterm Set III)

To determine the number of viable cells that are capable to absorb bacteria

To determine the number of fluorescent-labelled bacteria, phagocytes by a single phagocyte

To assess the formation of reactive oxygen species by Nitroblue tetrazolium reduction to formazans in phagocytes

To assess the formation of reactive oxygen species by substrate oxidation to a fluorescent compound in phagocytes

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A humoral response is targeted on:

Both thymus-dependent and thymus-independent antigens

Exclusively thymus-dependent antigens

Exclusively thymus-independent antigens

Exclusively pathogen antigens

Exclusively haptens

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After a density gradient PBMC isolation, the cell viability must be

assessed. The proper dye is

(Midterm Set III)

Nitroblue tetrazolium (NBT)

Blue formazans

Trypan blue


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A Peyer's patch, this is:

encapsulated organ of gastrointestinal tract lymphatic tissue

non-encapsulated structure of gastrointestinal tract lymphatic tissue

Waldeyer's ring component

A microfolded cell (M-cell)

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Select the set of surface antigens that best characterize NKT cells

(Midterm Set III)

CD3-, CD16+, CD45+, CD56+

CD3-, CD14+, CD16+, CD45+

CD3+, CD16+, CD45+, CD56+

CD3+, CD19+, CD45+, CD56+

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A test applied to detect the oxygen metabolism enzyme defect

should be:

50% hemolysis- CH50

Trypan blue uptake

Nitroblue tetrazolium reduction test (NBT)

Radioactive chromium release assay

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The set of antigens that comprise different cell molecules,

associated with its differentiation, maturation and function is

termed as

(Midterm Set III)





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A test that is NOT aimed for cell isolation is:

MACS (magnetic-associated cell sorting)

FITC (fluorescein induced T cell isolation)

FACS (fluorescence-associated cell sorting)

Density gradient cell centrifugation

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The innate immune components do not include

(Midterm Set IV)

NK cells

TCD4+ lymphocytes

mast cells


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Abnormal proportions of individual protein fractions observed in

the electrophoretic separation of serum proteins is termed:





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The antigen determinant, this is

(Midterm Set IV)

The paratope

An epitope

A portion of an antibodies that binds the epitope on the antigen

A portion of an antigen that binds the Fc portion of an antibody

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The antigen-antibody complex activates the complement in the


(Midterm Set IV)





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Adaptive immune response is characterized by

Specificity, receptivity, immunememory

Rapid answer, low plasticity

Specificity, diversity, immune memory

Unspecific, diversity, immune memory

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The FSC parameter in the flow cytometry, is related to

(Midterm Set IV)

The cell size

The cells granularity

The cell fluorescence intensity

The cell surface marker density

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After a density grading PBMC isolation, the cell viability must by

assessed. The proper dye is

nitroblue tetrazolium NBT

blue formazans

trypan blue


Fenster schliessen

1 Kommentare

  • 01.05.2020

Indicate the proper isotope control antibodies for antibodies planned to be used

in flow cytometry

(Midterm Set IV)

Mouse IgG2a, K Isotype, FITC labelled

Mouse IgG2b, K Isotype, APC labelled

Anti-CD3, Mouse IgG2b, K Isotype, FITC labelled

Mouse IgG2b, K Isotype, FITC labelled

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An antibody isotype classification results from differences in:

the position of certain ammoniac's in the Ab heavy chain

the position of certain aminocacids in the Ab light chain

the composition of the variable region of the Ab Fab portion

the composition of the Ab heavy and light chains in the constant region

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Phagotest in flow cytometry allows the assessment of

Phagocytes capacity of chemotaxis

Phagocytes capacity of proliferation

Phagocytes capacity of pathogen engulfment

Phagocytes capacity of pathogen intracellular killing

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An antigen binding site on an antibody molecule is formed by:

solid regions of heavy chains H and light chains L

variable regions of heavy chains H

light chain variable regions L

hypervariable regions of heavy chains H

hypervariable regions of heavy chains H and light chains L

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Mitogens are substances used for an in vitro assessment of

(Midterm Set IV)

Respiratory burst in phagocytes

Lymphocyte proliferation

Cell viability

Phagocyte chemotaxis capacity

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An Antigen Immunogenicity- this is:

Ability of binding to a specific soluble Immunoglobuline

Ability of binding to a a Immunoglobuline that constitute the B-cell receptor (BCR)

Ability to induce a specific Immune response

Ability to bind specific free Immunoglobulines and T-cell receptors (TCR)

Ability to bind the TCR exclusivelessly

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Superantigens can activate T cells in a particular way. This is

A TCR-MHC class I complex binding

A TCR-BCR complex binding

A TCR-MHC class II-complex binding

A Fas-FasL complex binding