Lernkarten

Karten 60 Karten
Lernende 9 Lernende
Sprache English
Stufe Universität
Erstellt / Aktualisiert 09.01.2019 / 29.04.2020
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0 Exakte Antworten 0 Text Antworten 60 Multiple Choice Antworten
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  • 15.01.2019
    Spermatogenesis in males requires the action of FSH and LH. Urofollitropin, which is purified from the urine of postmeno- pausal women, is used clinically to provide FSH activity. The answer is E.
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A young couple (25-year-old male, 23-year-old female) wants to start a family. They have not conceived after 1 yr of unprotected intercourse. Infertility evaluation revealed no abnormalities in the female partner and low sperm count in the male. Which of the following is a drug that is purified from the urine of postmenopausal women and is used to promote spermatogenesis in infertile men?

Desmopressin

Gonadorelin

Goserelin

Somatropin

Urofollitropin

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  • 15.01.2019
    Oxytocin is an effective stimulant of uterine contraction that is routinely used to augment labor. The answer is C.
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A 29-year-old woman in her 41st wk of gestation had been in labor for 12 h. Although her uterine contractions had been strong and regular initially, they had diminished in force during the past hour. Which of the following agents would be used to facilitate this woman’s labor and delivery?

Dopamine

Leuprolide

Oxytocin

Prolactin

Vasopressin

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  • 15.01.2019
    from immediate destruction, will help correct the IGF deficiency. Because of the inactive GH receptors, somatropin will not be effective. The answer is C.
  • 15.01.2019
    This child’s condition is due to the inability of GH to stimu- late the production of insulin-like growth factors, the ulti- mate mediators of GH effects. Mecasermin, a combination of recombinant IGF-1 and the binding protein that protects IGF-1 from imme
2

A 3-year-old boy with failure to thrive and metabolic disturbances was found to have an inactivating mutation in the gene that encodes the growth hormone receptor. Which of the following drugs is most likely to improve his metabolic function and promote his growth?

Atosiban

Bromocriptine

Mecasermin

Octreotide

Somatropin

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  • 15.01.2019
    Leuprolide is an agonist of GnRH receptors, whereas gani- relix is an antagonist. Although both drugs can be used to inhibit gonadotropin release, ganirelix does so immediately, whereas leuprolide does so only after about 1 wk of sustained activity.
1

An important difference between leuprolide and ganirelix is that ganirelix

Can be administered as an oral formulation

Can be used alone to restore fertility to hypogonadal men and women

Immediately reduces gonadotropin secretion

Initially stimulates pituitary production of LH and FSH

Must be administered in a pulsatile fashion

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  • 15.01.2019
    schizo- phrenia or other forms of psychotic illness. The answer is A.
  • 15.01.2019
    Bromocriptine,adopaminereceptoragonist, is used to treat the amenorrhea-galactorrhea syndrome, which is a consequence of hyperprolactinemia. Because of its central dopaminergic effects, the drug should not be used in patients with a history of
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A 27-year-old woman with amenorrhea, infertility, and galactorrhea was treated with a drug that successfully restored ovulation and menstruation. Before being given the drug, the woman was carefully questioned about previous mental health problems, which she did not have. She was advised to take the drug orally. Which of the following is most likely to be the drug that was used to treat this patient?

Bromocriptine

Desmopressin

Human gonadotropin hormone

Leuprolide

Octreotide

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  • 15.01.2019
    wasting syndrome. The answer is E.
  • 15.01.2019
    Its main use is as a diagnostic tool. GnRH can be used to treat infertil- ity. Somatropin, recombinant human GH, promotes growth in children with Turner’s syndrome (an XO genetic genotype) or chronic renal failure. It also helps combat the AIDS-associated
  • 15.01.2019
    Adrenocorticotropin (ACTH) is used diagnostically in sus- pected adrenal insufficiency. Corticotropin-releasing hormone (CRH) is used to distinguish Cushing’s syndrome from ectopic ACTH secretion. GHRH is rarely used as treatment.
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A 3-year-old girl was referred to the genetic counselor by her pediatrician. She presents with short stature (height is 85 cm, –3 standard deviations) and appears to have loose skin on her neck. Cytogenetic testing reveals an XO karyotype. Which of the following drugs will allow her to achieve a higher adult height?

Adrenocorticotropin (ACTH)

Corticotropin-releasing hormone (CRH)

Growth hormone-releasing hormone (GHRH)

Gonadotropin-releasing hormone (GnRH)

Somatropin

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  • 15.01.2019
    In precocious puberty, the hypothalamic-pituitary-gonadal axis becomes prematurely active for reasons that are not understood. Treatment involves suppressing gonadotropin secretion with continuous administration of a long-acting GnRH agonist such as leupr
1

A 3-year-old girl presented with hirsutism, breast enlargement, and a height and bone age that was consistent with an age of 9. Diagnostic testing revealed precocious puberty. Which of the following is the most appropriate drug for treatment of this patient’s precocious puberty?

Atosiban

Follitropin

Leuprolide

Octreotide

Pegvisomant

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  • 15.01.2019
    Octreotide, a somatostatin analog, has some efficacy in reducing the excess GH production that causes acromegaly. The answer is D.
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A 47-year-old man exhibited signs and symptoms of acromegaly. Radiologic studies indicated the presence of a large pituitary tumor. Surgical treatment of the tumor was only partially effective in controlling his disease. At this point, which of the following drugs is most likely to be used as pharmacologic therapy?

Cosyntropin

Desmopressin

Leuprolide

Octreotide

Somatropin