MMM, Tissue Engineering
MMM (4), Tissue Engineering
MMM (4), Tissue Engineering
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Cartes-fiches
TE components
- cells
- primary cells, genetically manipulated, stem cells
- scaffold
- bioactive, bioinert, resorpable
- biologial signals
- growth factors, environmental proteins, mechanical and electrical signals
Connective Tissue
SUPPORTING
bone, cartilage, fat, fibrous tissue
Epithelial Tissue
COVERING
skin, lines inner and outer surfaces of the body
Muscle Tissue
MOVING
produces mechanical force by contraction
Nervous Tissue
COMMUNICATING
conducts electrical signals
classes of organs
- flat tissue structure
- skin, cornea, cartilage
- tubular tissue structure
- trachea, oesophagus, blood vessels
- hallow tissue structure
- bladder
- solid organs
- kidney, liver, heart, pancreas
cell source
- autologous/autogenic
- allogenic
- syngenetic
- xenogenetic
autologous/autogenic
cells are from the patient itself
+ compatible, no rejection/immunologic response
- not a great amount can be taken from the patient itself.
syngenetic
donor is the twin sibling (same genetical disposition)
+ no immunological reaction
- need to have twin
allogenic
the donor is a non-related human
+ younger donors can help, more potent cells
- immunological reaction/rejection
xenogeneic
cells are from another species (pig)
- tissue needs to be decellularized before
- rejection/immunological reaction
- transfer of animal diseases to the human
+ umlimited supply from young animals
