Lernkarten

- Protection, solation
- Compartimentalization
- Communication, interface with external environment
- Gates, water & solutes transport

s.B.

s.B.

Non-gated channels = channels that are always open

Teil einer Synapse

Six connexins assemble to form a connexon

Connexons in the plasma membrane of the cell lign with the connexons of an adjacent cell, forming a hydrophilic channel between two cytoplasms.
-> two connexons form a channel

connexons provide:
• Size selectivity
• Open-closed conformation

• The boundary of cells is mostly constituted of a lipidic material
• Non-lipophilic substances (incl. water) must use specific pathways

Channel-like Integral Membrane Protein

-> Extremely abundant in RBCs (redbloodcells)

-> billions of water moleclues can cross the pore per second