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Flashcards	463
Language	English
Category	Medical
Level	University
Created / Updated	23.06.2022 / 01.08.2022
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26. Which reactions are the examples of phase I reaction in drugs metabolism

1. hydrolysis

2. reduction

3. glucuronidation

4. oxidation

A) only 4

B) only 1, 3

C) only 2, 4

D) only 1, 2, 4

E) all answers are correct

27. Which statement about renal excretion of drugs is NOT true

A) weak acids are more rapidly excreted in alkaline urine

B) weak acids may be passively secreted into the renal tubule

C) drugs bound to plasma proteins do not cross glomerular filter freely

D) weak basis may be actively secreted into the renal tubule

E) lipid soluble drugs are passively reabsorbed in the tubule

28. Which local anesthetic is an esther type

1. benzocaine

2. procaine

3. lidocaine

4. tetracaine

A) only 4

B) only 1, 3

C) only 2, 4

D) only 1, 2, 4

E) all answers are correct

31. Which drugs may decrease intraoccular pressure

1. pilocarpine

2. timolol

3. atropine

4. latanoprost

A) only 4

B) only 1, 3

C) only 2, 4

D) only 1, 2, 4

E) all answers are correct

32. Which beta blocking drug has additional alpha-blocking activity

1. proprano

2. metoprolol

3. nebivolol

4. carvedilol

A) only 4

B) only 1, 3

C) only 2, 4

D) only 1, 2, 4

E) all answers are correct

33. To the adverse effects of depolarizing drugs belong

1. prolonged paralysis

2. postoperative muscle pain

3. bradycardia

4. potassium release from muscle cells

A) only 4

B) only 1, 3

C) only 2, 4

D) only 1, 2, 3

D) all answers are correct

34. Which statement about non-depolarizing neuromuscular-blocking(?) drugs are NOT true

1. are competitive antagonists.... (? ? ?)... receptors in muscles

2. produce muscle fasciculation

3. are hydrolyzed by plasma cholinesterases

4. some may release histamine from mast cells

A) only 1

B) only 1, 4

C) only 2, 3

D) only 1, 2, 3

E) only 2, 3, 4

35. Bronchoconstriction, bradycardia, cardiac depression, fatigue and cold extremities are characteristic adverse effects for

A) beta-blocking drugs

B) alpha-blocking drugs

C) alpha-adrenomimetic drugs

D) cholinolytic drugs

E) none of the listed above

Which drugs don’t cause changes to tongue

Biotin

Niacin

Vit B1

Vit B2

Vit B3

Which drug used to treat hypothyroidism

Levothyroxine

Propanyluracil

Which of the following drugs could you give to a smoker women on the contraceptive pill

Ethinyl

Levonorgestrol

Estrone

Cyclosporine A not used for which of the following

Rheumatoid arthritis

Crohn’s disease

Posterior + something uveitis (non-infectious etiology)

Some other autoimmune disease

Dilated cardiomyopathy

Adverse effecrf not connected to progestins

Acne

Androgen effect

Bleeding

Depression

Orthostatic hypotension

Patient with myoglobinuria and hyperkalaemia following use of neuromusclar blocking agent. Which one?

Succinylcholine

Rapacuronium

Alpacuronium

B+C

None of the above

Androgens cannot be used in treatment of

Anaemia

Prostatic carcinoma

Endometriosis

1. (Statement 1) Abrupt cessation of glucocorticoid treatment after prologning theraoy is contraindicated because (statement 2) it can evoke acute adrenal insufficiency

a) first statement is true, second statement is false

b) both statements are false

c) both statements are true and there is a logical connection between them

d) both statements are true but there is no logical connection between them

e) first statement is false, second statement is true

2. Which of the following is a toxic effect associated with long-term glucocorticoid treatment?

a) hepatotoxicity

b) precocious puberty in children

c) a "lupus-like" syndrome

d) adrenal gland neoplasm

e) osteoporosis

9. Substances decreasing Fe (ferrum) absorption include all listed below EXCEPT:

a) cholestyramine

b) vitamin C

c) antacids

d) tetracyclines

e)cacao +tea + coffee

10. Which combination of drug and INCORRECT:

a) romiplostim - thrombocytopenia

b) sargramostin - stem cell transplantation

c) erythropoietin - anemia

d) filgrastin - neutropenia

e) oprelvekin - granulocytopenia

11. Which drug is most likely to be useful in the treatment of inflammatory bowel disease?

a) mesalamine

b) ursodiol

c) diphenhydramine

d) diphenoxylate

e) ondansetron

12. Which drug is most appropriate for the treatment of a patient who presents with Zollinger- Ellison syndrome resulting from a gastrinoma?

a) omeprazole

b) ranitidine

c) aprepitant

d) metoclopramide

e) ondasetron

13. Characteristic adverse effect of overdose is:

1. diarrhea

2. cough

3. acute renal failure

4. respiratory distress

a) only 2 and 3

b) all answers (1-4) are correct

c) only 4

d ) only 1 and 4

e) only 1, 2 and 4

14. During treatment with opioifd high degree of tolerance may develop to:

1. sedation

2. convulsion

3. miosis

4. nausea

a) only 2 and 3

b) all answers (1-4) are correct

c) only 4

d) only 1 and 4

e) only 1, 2 and 4

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