Pharma M2
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Flashcards
CNS stimulant used in management of narcolepsy or attention-deficit disorder
Inhibitor of angiotensin converting enzyme
Vasodilator used to manage hypertensive emergencies:
Most common side effect of oral beta-2 receptor agonists
Primary receptor type at autonomic ganglia:
Vesicular protein important in docking with the presynaptic membrane:
Rate-limiting step in acetylcholine synthesis:
Inhibits choline transport into cholinergic vesicles
Clostridium toxins:
Denervation supersensitivity in skeletal muscle is mainly due to:
Enzyme responsible for acetylcholine synthesis:
Effect of atropine on the heart:
Essential cofactor for the enzyme dopamine beta-hydroxylase:
Mechanism of cellular resistance to polyfunctional alkylating drugs:
Does not have direct vesicant effects:
Polyfunctional alkylating agent used specifically for chronic myeloid leukemia:
Major toxicity of alkylating drugs:
Most common route of administration for melphalan (Alkeran):
Nitrosourea with minimal bone-marrow suppression and effective in treating pancreatic, islet cell carcinoma.
Used in combination with vinblastine and bleomycin: a major advance in treating nonseminomatous testicular cancer:
Anticancer drug that is also used to treat psoriasis and rheumatoid arthritis:
Recommended for treating hairy cell leukemia
This pyrimidine analog is used systemically to treat adenocarcinomas, topically for skin cancer and works through inhibition of DNA synthesis.
Derivative from the Western Yew and European Yew tree, this anticancer drug acts by enhacing tubulin polymerization.
Chemotherapeutic (anticancer) dosing principles:
Most important toxic effect associated with alkylating agents:
Nerve terminal reuptake inhibitor
Orthostatic (postural) hypotension
Phase of the cardiac action potential that principally determine heart rate
Centrally-acting antihypertensive drug
