Microbiology TEST 1
Microbiology 4th Semester
Microbiology 4th Semester
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Lernkarten
Early-onset listeriosis causes
- appears in first 3 trimester
- stillborn, premature birth
- severe form of early-onset is granulomatosis infanti-septica - high mortality
granulomatosis infanti-septica - (abscesses and granulomas in multiple organs)
Late-onset listeriosis causes
- older than >1 week - meningo-encephalitis or meningitis
- approx. a week - sepsis
WATCH OUT SIMILAR to GBS (S.agalactiae)
Healthy Adults having food-poisoning with listeria monocytogenes have what sort of clinical symptoms ?
- either asymptomatic or
- flu-like
- acute self-limiting gastroenteritis in some patients
IS A NON-INVASIVE form of listeriosis
Name the non-invasive listeriosis caused by listeria monocytogenes
- gastroenteritis
Name the invasive listeriosis caused by listeria monocytogenes
- in risked groups like : neonatals, pregnant woman, elderly >50, immunosuppressed
- pregnant woman - septicemia / nonspecific influenza-like sym.
- neonatals - early onset listeriosis = stillborn, premature birth / severe form - granulomatosis infanti-septica
- neonatals - late onset listeriosis = meningitis / menigoencephalitis
- immunosuppressed & elderly >50 - meningitis
Ery-si-pelo-thrix rhusio-pathiae has a specific risk group name it:
- occupation exposure - like butcher,veterinarians, farmers
Ery-si-pelo-thrix rhusio-pathiae has 4 virulence factors name them
- neura-mini-dase - adhesion and penetration into epithelial cell
- capsule -protected from phagocytosis
- adhesions
- hyaluronidase
Ery-si-pelo-thrix rhusio-pathiae reservoir is ?
- herbivores (swine/turkey)
- environment
Ery-si-pelo-thrix rhusio-pathiae transmittion ?
- Zoonosis - from animal to human
- through skin abrasion or cut during handling with animal products
Ery-si-pelo-thrix rhusio-pathiae what are the clinical diseases ?
- localized cutaneous infection - called ERYSIPELOID (dont mix it with erysipelas)
- generalized cutaneous infection
- Uncommon but may appear = septicemia - associated with endocarditis
Ery-si-pelo-thrix rhusio-pathiae causes ERYSIPELOID what are the hallmarks ?
- on fingers or hands has a violet color (violaceous) + raised edge
- slowly goes peripherally and center turns white (discoloration - violet color moves to the edges)
- systemic signs but blood cultures are negative
Ery-si-pelo-thrix rhusio-pathiae develops erysipeloid and streptococcus pyogenes develops erysipelas what is the clinical difference ?
- erysipelas - has suppuration
- erysipeloid - does not have suppuration
Cutibacterium (C. acne / C. granulosum) reservoir ?
- Endogenous - Human skin and mucosal surfaces, Genitourinary Tract, Oral Cavity
- sebaceous glands, hair follicles,
Cutibacterum (C. acne / C. granulosum) Virulence factors ?
- Low Virulence Factors
- biofilm - infection of deep seated implantable devices
- produce acids - propionic , acetic , lactic , catalase
Cutibacterium (C.Acne / C. granulosum) is a slow-grower therefore clinical diseases can appear ?
- within 2 years - like acne
Cutibacterium (C.acne und C. granulosum) are
Enterotoxin A in S. Aureus causes what
enterocolitis
