Microbiology TEST 1
Microbiology 4th Semester
Microbiology 4th Semester
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Lernkarten
Streptococcus pyogenes has 6 extracellular strucutres name them:
- streptokinase - plasminogen>plasmin>fibrinogen>fibrin>lysing fibrin clots> rapid spread of S.pyogenes
- superantigens (PSE -pyrogenic streptococcal exotoxin) - A,B,C & F - secreting excessively cytokines
- streptolysin O - oxygen-labile > lyses RBC, Leukocytes & platelets
- Streptolysin S - O2-stabile > lyses RBC, Leukocytes & platelets
- Hyaluronidase
- Fibronectin-binding proteins
streptococcus pyogenes has 5 enzymes helping to cause direct invasion name them:
- streptolysin O - oxygen-labile > lyses RBC, Leukocytes & platelets> is antigenic
- Streptolysin S - O2-stabile > lyses RBC, Leukocytes & platelets > is not antigenic
- Hyaluronidase
- Fibronectin-binding proteins
- streptokinase - plasminogen>plasmin>fibrinogen>fibrin>lysing fibrin clots> rapid spread of S.pyogenes
Streptococcus Pyogenes can be
Transmission of Streptococcus Pyogenes is
most common diseases of streptococcus pyogenes in children
Streptococcus Pyogenes is susceptible to DRYING true or false?
Streptococcal pharyngitis caused by Streptococcus pyogenes causes?
What is the Complication of streptococcal pharyngitis caused by streptococcus pyogenes
Scarlet fever:
- due to superantigen - PSE = pyrogenic streptococcal exotoxin
- within 1-2 days after initial clinical symptoms of pharyngitis develop, a diffuse erythematous rash initially appaers on UPPER CHEST & SPREADS to EXTREMITIES
Scarlet fever appears by infection of streptococcus pyogenes what are its characteristic symptoms?
Strawberry tongue appears in streptococcus pyogene, its characteristic for Scarlet fever and discribed:
Streptococcus pyogenes has the enzyme Streptolysin S that
Invasive or suppurative diseases of streptococcus pyogenes are:
suppurative diseases - pus forming diseases
Skin infection in streptococcus pyogenes are:
skin infection of streptococcus pyogenes are transmitted by:
- erysipelas
- cellulitis
- pyoderma
- necrotising fasciits
- folliculitis
- bullous impetigo
pyoderma in streptococcus pyogenes:
Erysipelas is a skin infection of streptococcus pyogenes
necrotising fasciitis is a remarkable invasive/acute infection of soft tissue caused by streptococcus pyogenes:
necrotising fasciitis is a remarkable invasive/acute infection of soft tissue caused by streptococcus pyogenes and is also named:
flesh-eating bacteria
Necrotising fasciitis caused by streptococcus pyogenes can lead to toxicity, multiorgan failure and death is that true or false?
Toxic shock syndrom in streptococcus pyogenes is different to staphylococcus aureus TSS why?
Toxic shock syndrom differences btw streptococcus pyogenes and staphylococcus aureus
staphylococcus aureus:
- is caused by superantigen: TSST-1
- due to use of tampon when left in place for long time
- in vagina or wound
streptococcus pyogenes:
- is caused by superantigen: PSE -pyrogenic streptococcal exotoxin
- patient may have necrotising fasciitis
- patient has bacteremia
- introduction due to break in skin
- increased risk for immunosuppressed patients
ARF and RHD stands for what disease in streptococcus pyogenes?
ARF - Acute Rheumatic Fever - causes inflammatory lesions in joints, especially heart, blood, connective tissue etc
RHD - Rheumatic Heart Disease - is a reaction with antibodies actually thought for antigenes of streptococcus pyogenes but also cross-react with antigenes of the HEART causing rheumatic fever
Name the 2 antibody-mediated or non-suppurative diseases of streptococcus pyogenes:
Rheumatic fever in streptococcus pyogenes:
Rheumatic fever in streptococcus pyogenes 6 manifestations are ?
- fever
- chorea
- joint sweling (arthritis)
- myocarditis
- subcutaneous nodules
- erythema marginatum
Rheumatic fever is caused by streptococcus pyogenes explain the reason why it is antibody-mediated disease ?
- ß-hemolytic streptococci pyogenes (GAS) have similar antigenes to that of the hearts antigenes
- therefore when antibodies released to attack streptococcus pyogenes, the also cross-react with antigenes of the heart
- causin inflammatory myocarditis
- and chronic progressive damage to the heart valves especially the mitral and aortic valve
Acute Glomerulo-nephritis is caused by streptococcus pyogenes:
Acute Glomerulo-nephritis is caused by streptococcus pygoenes (GAS) is it antibody-mediated disease/nonsuppurative ?
The sequela of Acute Glomerulo-nephritis is caused by streptococcus pygoenes (GAS) through ?
sequela - spätfolge / Folgeerscheinung
" sequela" means?
spätfolge / Folgeerscheinung
Streptococcous AGALACTIAE is
Streptococcus agalactiae causes severe diseases in NEONATES
Streptococcus AGALACTIAE has specific virulence factors name them:
HINT - name three
- polysaccharide capsule - antiphagocytic
- glycocalyx and pilli - adhesion
- Glycosyl-transferase - invasion of blood-brain barrier
To remember : PGGP
Streptococcus AGALACTIAE is part of natural flora and colonize the :
- lower gastrointestinal tract
- genitourinary tract
Staphylococcus Agalactiae colonization with supsequent development of disease in the neonate can occur:
- in utero
- during birth
- during first months of life
Streptococcus agalactiae causes disease in woman
Streptococcus agalactiae causes disease in pregnant woman:
Streptococcus Agalactiae causes in general in adults what type of diseases?
Streptococcus Agalactiae causes in general in adults what type of diseases?
NAme: 7
- postpartum endometritis
- Urinary tract infection
- pneumonia in immunosuppressed patients
- bone and joint infections
- soft tissue infections
- septicemia
- endocarditis
Streptococcus pneumonia is
