ECNR 4 Athens4
4 Kurs Brain Trauma
4 Kurs Brain Trauma
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CNs reaction chemo
Glial, Neurons, vascular
SMART syndrom
Damage to the endothelian Fells afeter radiationn
SMART syndrome, a catchy acronym for the otherwise unwieldy stroke-like migraine attacks after radiation therapy, is an uncommon complication of cerebral ...
Liquorfluss durch aequeduct per Heart Beat
30 ul
Where ist liquor absorbedt?
Capillary bed - not pacchionic Granulationen
Funktion pacchionic granulations?
After closure of Kalotte they are Pressure Controllers
Classification Hydrozephalus
Akute obstructiv h
communicating h
- Caused Anything that restriktiv art pulsation
vasculitis
ectasia
spasm
diabetic microangiopsthis
small vessel disease
Classification Hydrozephalus
Akute obstructiv h
communicating h
- Caused Anything that restriktiv art pulsation
vasculitis
ectasia
spasm
diabetic microangiopsthis
small vessel disease
Spektroskopie Tbc
Lipids
Tbc in Images
T2 dark
basal Meningitis
infarkts
arteritis 40%
Wegener granulomatosis
Vasculitis small and Medium vessel
less cns , nerve 2,6,7, meninges
mortality high untreated - immunotherapy
Neurosarkoidosis
Cns 10%
afroadricans 2,4%
intravranial lesions T2 hypointens to Gary matter (gliosis)
spinal T2 hyperintense (inflammation)
Lymphoid granulomatosis
Angiocentric
b-cell proflifaration
angiostructiv lymphoreticular Proliferation lung but also cns
rare (19 Patienten with cns)
masslike, infiltrating lesions
Krankheiten die menignen, nerven und Parenchym befallen
Neurosarkoisosis
wegener
lymphoid granulomatosis
Infektion 1 and 2 Trimester
Malformation
Infektion 3 Trimester
Clastic lesions
calzifiation
germinolysis
Hydrozephalus
TORCH
Toxoplasmosis
rubella
cmv
herpes, hiv
Toxoplasomis fetal?
Porencephaly
kalzifikation
HIV fetal
Calcifiaktion BG
leukencephakopathy
atrophie
Most Common Infektion in childhood
Meningitis
leptomenieal vasculitis
Extension vichow to Brain
cerebritis
abszess, ependymatitis
Difference ADEM spine to MS
More than 3 vertebral Body
SCIWORA before which Age?
8 years
spinal Cord Injury without radiologic evidence of abnormality
SCIWORET?
Spinal Cord injury WithOut Radiologic Evidence of trauma
elderly
Vascular ischemia in defneration myleopahtie
Central edema in spine
Vasogenic oedema in Central grey matter
embolisme
neuromylitis optica
central Canal is vascular borderzone - ischemia, Eulenaugen
Fibrocartilagenous embolus?
Discherniation enters radical arterie - ischemia
Myelopahtie Vit B12?
Posterior column
fasciculus cuneatus et gracilis
Longitudinal transverse myelitis
More than 3 verterbL
central
hole cord
MS Risk: 2%
Partial transverse myelitis
> 2 vertebral
excentric
local
Not hole diameter
ms, ADEM, NMO(Devic)
NMO?
Neuromeylits optica
not ms
more than 3 vertebral
opticus neurotis
AK against Aquaporin 4 channel
60% of Cases with Brain lesions
Chronik Form Giuliani barre
Chronik idiopathic demyelination polyneuropathi
CIDP
Central vein Sign?
SWI spezific for ms
Criteria for NMO
Spine more than 3 vertebral
bilateral optic Optik neuritis
1 periductal lesion
Normal appearing white matter
Ist nicht normal in ms
CBV,CBF low
Magnetitstion Transfer low
ADC hoch
- > diffuser Befall
PML
HIV
MS natalizumab
JC- Virus
u-fibers
flacjig
no enhancemnd, butwith natalizumab can enhanced 40%
DWI ring like
CAVE PML-IRIS (hypoperfusion) - First worsening
Dysmyelinitaion
Subcortical erhalten
periventricular defect
Hypomyeliniation - Periventricular and subcortical sparing
Typical Peak in demyelination disease
Succinate elevated
latatat unspezifisch
Mitochondrial disease vererbt durch wen?
Mutter, weil Eizellen nur mito behalten
je nach Ausprägung der falschen mitos verschiedene auspraegung der Krankheit
Mitochondrial diseases?
Leigh disease - BG and Brainstem, symmetrical, sek Atrophie
MELAS - mito enceph laktat acidosis and stroke like , Migration stroke, Calcium in BG
mitochondrial disisease have preference for cerebellum
Hypointens lesions in T2
Fungus
tbc, sarkoid
lymphoma
Spontanous intra Hypotension
Intrakraniell CSF 150
spjnal 50
hyophysenoedem
dilatation venen
optic oedema
pressure CFS 65 h2o
SISCOM
Interictal and ictal SPECT
A method for advanced imaging of epilepsy patients has been developed with Analyze at the Mayo Foundation which uses a combination of SPECT and MRI imaging for improved diagnosis of areas of regional activation in the brain during seizure. This technique, called SISCOM, for Subtraction Ictal SPECT COregistered to MRI,
fMRI Lokalisation of eloquent Cortex
