Pharma quizzes

Pharma teams quiz

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About these flashcards

This flashcard set is tailored for university-level medical students, focusing on the mechanisms, effects, and treatments of various drugs. It covers key topics like drug actions, adverse effects, and specific treatments for conditions such as Zollinger-Ellison syndrome and inflammatory bowel disease. The set is particularly useful for those preparing for exams or seeking a deeper understanding of pharmacology, as it provides detailed insights into drug interactions, receptor activities, and patient-specific considerations.

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Which diuretic is potassium-sparring agent?

a)toresemide

b)hydrochlorothiazide

c)acetazolamide

d)amiloride

Ketamine:

A - produces "dissociative anesthesia"

B - is cardiovascular stimulant

C - has analgesic activity

a)A and C

b)B and C

c)A and B

d)A, B and C

What is true about local anesthetics?

A - are weak bases

B - open sodium channels

C - are sometimes used with norepinephrine

a)A and B

b)A and C

c)B and C

d)A, B and C

Which is long-acting local anesthetic?

A - tetracaine

B - bupivacaine

C - ropivacaine

a)A, B and C

b)B and C

c)A and B

d)A and C

Which inhaled anesthetics are almost not metabolized?

A - halothane

B - desflurane

C - isoflurane

a)A, B and C

b)A and B

c)B and C

d)A and C

Which is intermediate-acting neuromuscular blocking drug?

A - pancuronium

B - rocuronium

C - vecuronium

a)A and C

b)A, B and C

c)A and B

d)B and C

Which drugs may inhibit aldehyde dehydrogenase?

A - disulfiram

B - glibenclamide

C - cefamandole

a)A, B and C

b)A and B

c)A and C

d)B and C

What is NOT true about resins?

a)reduce pruritus in cholestasis

b)increase vitamin K absorption

c)bind bile acids

d)are nonabsorbable polymers

Which drug may be used in both hypercholesterolemia and phytosterolemia?

a)fenofibrate

b)mipomersen

c)atorvastatin

d)ezetimibe

What is used in the treatment of alcohol dependence?

A - thiamine

B - naltrexone

C - acamprosate

a)A and C

b)A and B

c)B and C

d)A, B and C

What is true about unfractionated heparin?

a)converts plasminogen to plasmin

b)belong to thrombolytic agents

c)during the treatment INR should be monitored

d)complexes with antithrombin III

What is used in the treatment of methanol poisoning?

A - ethanol

B - fomepizole

C - ethylene glycol

a)B and C

b)A and B

c)A and C

d)A, B and C

The primary use of cilostazol is:

a)prevention of stroke

b)bleeding in hemophilia A

c)intermittent claudication

d)deep vein thrombosis

Which is NOT the action of fibrates (direct or indirect)?

a)decreased fatty acids oxidation in the liver

b)decreased secretion of triglycerides

c)hydrolysis of VLDL in blood

d)increased activity of LPL

What is the least probable adverse effect of warfarin?

a)thrombocytopenia

b)bleeding and bruisiness

c)teratogenic action

d)transient hair loss

Increased risk of gallstones formation is observed during the treatment with:

a)fenofibrate

b)colestipol

c)rosuvastatin

d)ezetimibe

Evolocumab:

a)inhibits MTP

b)inhibits PCSK9

c)activates lipoprotein lipase

d)activates PPAR-gamma

Which drug is an oral direct thrombin inhibitor?

a)fondaparinux

b)rivaroxaban

c)bivalirudin

d)dabigatran

What should be regularly monitored during their treatment with rosuvastatin?

a)creatinine clearance

b)plasma calcium level

c)liver transaminases

d)platelet count

In the treatment of acute coronary syndromes is NOT used:

a)abciximab

b)idarucizumab

c)tirofiban

d)eptifibatide

Which drugs are NOT an antiplatelet agent?

a)dipyridamole and abciximab

b)tranexamic acid and alteplase

c)acetylsalicylic acid and clopidogrel

d)tirofiban and eptifibatide

Which drug is not reused due to the risk of hypersensitivity?

a)reteplase

b)tenecteplase

c)streptokinase

d)alteplase

Which drug has the least, or even no significant effect on warfarin anticoagulant activity

a)fluconazole

b)paracetamol

c)aspirin

d)disulfiram

Which statin should be given in the evening?

a)pitavastatin

b)fluvastatin

c)atorvastatin

d)rosuvastatin

Which drug may be used in the treatment of life-threatening thrombosis or purpura fulminans?

a)vitamin K

b)desmopressin acetate

c)cryoprecipitate

d)protein C concentrate

Use of red yeast rice should be not recommended in hyperlipidemia because all of the reasons EXCEPT:

a)may significantly decrease plasma glucose level

b)some preparation may contain nephrotoxic citrinin

c)contains many poorly studied organic compounds

d)statin content is very variable

Which substance belongs to hallucinogens?

A - mescaline

B - flunitrazepam

C - LSD

a)A and C

b)A and B

c)B and C

d)A, B and C

Which drug is no longer recommended because of unfavorable benefit-risk ratio?

a)micronized fenofibrate

b)ezetimibe

c)niacin

d)rosuvastatin

What is NOT true about colestipol?

a)binds bile acids in the liver

b)interferes with the absorption of some vitamins

c)increases cholesterol catabolism

d)may be used in digitalis toxicity

What is true about ticagrelor

a)inhibts synthesis of II, Vll, IX and X of clotting factors

b)inhibits PDE3 activity

c)inhibits directly factor Xa activity

d)reversible blocks AP receptors

Withdrawal of which of the listed substances may cause less or more pronounced withdrawal

syndrome?

A - morphine

B - amphetamine

C - marijuana

a)B and C

b)A and B

c)A, B and C

d)A and C

Torsades de pointes is the LEAST probable during the treatment with:

a)dofetilide

b)verapamil

c)procainamide

d)amiodarone

Which antidepressant is approved for the treatment of premenstrual dysphoric disorder?

a)buspirone

b)doxepin

c)sertraline

d)imipramine

A combination of eplerenone with all listed drugs increases the risk of hyperkalemia EXCEPT:

a)torasemide

b)valsartan

c)trimethoprim

d)triamterene

Sertraline blocks:

a)NET

b)DAT

c)SERT

d)AChE

Which drug inhibits serotonin and norepinephrine reuptake?

A - venlafaxine

B - duloxetine

C - amitriptyline

a)B and C

b)A and C

c)A, B and C

d)A and B

Which drug used in the treatment of arterial hypertension may cause marked sedation?

A - methyldopa

B - indapamide

C - clonidine

a)A and C

b)A and B

c)B and C

d)A, B and C

Which beta adrenolytic is NOT registered for congestive heart failure?

a)carvedilol

b)nebivolol

c)metoprolol modified release

d)atenolol sustain release

Which receptors may be blocked by tricyclic antidepressants?

A - muscarinic

B - alpha-1 adrenergic

C - serotonin 5-HT₃

a)B and C

b)A and C

c)A and B

d)A, B and C

What is NOT the characteristic adverse effect of verapamil?

a)exacerbation of heart failure

b)constipation

c)reflex tachycardia

d)pretibial edema

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