Cell Biology

Structure, Plama Membrane, Transport, Cytoskeleton, Motor Proteins, Endomembrane System

Structure, Plama Membrane, Transport, Cytoskeleton, Motor Proteins, Endomembrane System


S. B.
This flashcard set delves into the intricate world of cell biology at a university level, focusing on the structure and function of various cellular components. It covers key topics like the endomembrane system, cytoskeleton elements such as microtubules and microfilaments, and the roles of proteins like kinesin and dynein in cellular transport. The set also explores different types of transport mechanisms, including active and passive transport, as well as the functions of organelles like ribosomes, vesicles, and the endoplasmic reticulum. This comprehensive collection is ideal for students and researchers seeking to understand the fundamental processes and structures within cells, providing a solid foundation for advanced studies in biology.
Karten
59
Lernende
1
Sprache
Englisch
Kategorie
Biologie
Stufe
Universität
Erstellt / Aktualisiert
02.01.2020 / 11.01.2020

Cartes-fiches

Carrier proteins 

interact with molecule->undergo a shape change to transport the molecule on the other side of the membrane

Active transport 

Molecule and ATP attach to carrier protein, Uses ATP to transport molecules against concentration gradient (use of carrier proteins)

Molecules passing thorugh simple diffusion (2 types)

1. Hydrophobic molecules (O2 and N2) 2. Small uncharged polar molecules (H2O,CO2, Urea, Glycerol)

Primary active transport 

Direct hydrolysis of ATP and against concentration gradient (Sodium(out)-Potassium(in) Pump)

Secondary active transport

Uses indirect ATP from primary transport (energy supplied by ion concentration and electrical gradient from primary active transport)

Bulk transport 

Large substances which can't be transported through channel proteins or diffusion enter or leave cells via bulk transport (endocytosis&exocytosis)

Phagocytosis (function, energy, membrane peaks (term), how it works)

Transfer of large substances or bacterias into the cell, requires ATP, pseudopodia surrounds particle and takes it into cell (called phagosome)

Pinocytosis (function, energy)

Bulk transport of liquids via vesicles, requires ATP

Clathrin mediated endocytosis 

Special endocytosis which has receptors to which only specific substances can bind and then get transported in the cell

Exocytosis 

Golgi apparatus produces secretory proteins (early endosomes) which move to plasma membrane and get secreted via exocytosis

Microfilaments (cytoskeleton) (structure,content, function (2), length)

Strands with + and - end, made of actin (protein), major way of movement inside the cell, important for contractile movement, 7nm

Microtubules (cytoskeleton) (structure, content, function, length, direction)

Hollow cylinders with + and - end , made of alpha&beta tubulin monomers = tubulin dimer -> many molecule of tubulin, moves vesicles, organelles and chromosomes around the cell, 25nm, retrogade (moving towards negative end)

Intermediate filaments (cytoskeleton) (structure, content, function)

Rope like assemblages, fibrous proteins, stabilisation and shape maintenance of cell

Myosin (microfilament in cytoskeleton) (definition,function (2)

Motor protein, crosslinks actin filaments (microfilaments) with each other (cell movement), contraction and relaxation of muscle fibre,

Dynein (microtubule in cytoskeleton) (definiton, groups(2), 

Motor protein, axonemal (sliding of microtubules within cilia&flagella) & cytoplasmic (transport&position organelles and assemble centrosomes)

Dynein and Microtuble interaction (2)

Dynein between two microtubule causes tubules to slide, Dynein crosslinked with nexin causes tubules to bend

Kinesin (function, transport types(2))

Same as Dynein but "anterogade" (towards positive end), 1. Axonal transport (organelles within neurons), 2. Cargo transport (transport&position organelles and assemble centrosomes)

Kinesin and Microtubule interaction 

Kinesin "walks" on microtubules transporting cargo or axonal organelles towards positive end, one foot deattaches and reattaches

Endomembrane system (parts (4) with processes)

1. rER:

  • Ribosomes on membrane synthesize proteins 
  • Proteins are then modified (glycosylated)
  • Membraneous sections pinch off to form vesicles

2. Vesicles:

  • Vesciles transport cargo to the golgi apparatus 

3. Golgi apparatus: 

  • Vesicle fuse with membrane of cis golgi and deliver proteins 
  • Proteins get modified by golgi specific (membrane bound) enzymes moving to medial and trans golgi sections
  • Membraneous section of trans golgi pinch off to form vesicles that carry them to cellular destination (example: secretion)

 

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